Direct Nucleophilic Substitution of Alcohols Using an Immobilized Oxovanadium Catalyst

نویسندگان

چکیده

Abstract Direct nucleophilic substitution of alcohols with thiols or carbon nucleophiles was achieved using a mesoporous silica‐supported oxovanadium catalyst (VMPS4). Benzyl and allyl were compatible in this reaction under mild conditions, affording the products high yields. The VMPS4 showed excellent chemoselectivity toward presence acid‐labile functional groups, which is contrast to that observed for commonly used Lewis acid catalysts, exhibit poor selectivity. could be recycled by simple centrifugation, catalytic activity maintained over seven cycles.

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ژورنال

عنوان ژورنال: European Journal of Organic Chemistry

سال: 2021

ISSN: ['1434-193X', '1099-0690']

DOI: https://doi.org/10.1002/ejoc.202100569